In the evening, apply 4‐5 drops to clean dry skin, avoiding the eye area. Allow product to absorb before applying other skincare products. Limit initial use to once or twice a week, gradually increasing frequency to every other night, then every night as tolerated. It is important to establish consistent skin tolerance before advancing to a higher concentration.

Retinol may increase photosensitivity. Always use a high-protection, broad spectrum sunscreen when using this product.

As a precaution, retinol cream products should not be used by pregnant women or women who intend to become pregnant in the near future. Though there are no reports of topical retinol having any negative effect on fetal development, always consult a physician.